Lymphedema

What you need to know about Lymphedema.

THE LYMPHATIC SYSTEM AND LYMPHEDEMA

The lymphatic system is a network of tissues and organs that help rid the body of toxins, waste and other unwanted materials. The primary function of the lymphatic system is to transport lymph, a fluid containing infection-fighting white blood cells, throughout the body.

The lymphatic system primarily consists of lymphatic vessels, which are similar to the veins and capillaries of the circulatory system. The vessels are connected to lymph nodes, where the lymph is filtered. The tonsils, adenoids, spleen and thymus are all part of the lymphatic system.

Lymphedema is a condition where lymph fluid accumulates in the soft tissues, often in the arms or legs. Lymph fluid is filtered by the lymph nodes prior to entering the bloodstream. The lymphatic system is susceptible to blockages.  When the lymph nodes become obstructed, lymph fluid does not drain properly and that fluid build up leads to progressive swelling.

There are two kinds of lymphedema:

  1. PRIMARY LYMPHEDEMA — occurs on its own.
  2. SECONDARY LYMPHEDEMA — occurs as a result of some other disease or condition.

The lymphatic system — part of the immune system — moves lymph fluid carrying substances harmful to the body through the lymph vessels. When this fluid eventually reaches the lymph nodes, waste products are filtered by infection-fighting cells that live in your lymph nodes called lymphocytes (also known as T-cells and B-cells). Ultimately, germs such as viruses, bacteria, and fungi are flushed from body in this manner.

Secondary lymphedema is far more common than primary, but both involve a disruption within the lymph nodes and/or vessels. While there is no cure for lymphedema at the present time, this condition can be managed with early diagnosis and care of the affected limb(s).

CAUSES FOR LYMPHEDEMA

The cause for primary lymphedema involves failed or faulty development of the lymph vessels and/or lymph nodes. While developmental deficiencies of the lymph vessels and/or lymph nodes may be present at birth, the associated symptoms may not show until later in life. The condition is most likely to manifest in the legs but the entire body can be affected. Also, women are more susceptible to primary lymphedema than men.

The cause for secondary lymphedema is usually injury, surgery, or complications from the destruction of lymph nodes or lymph vessels. This type of lymphedema can occur as a direct result of radiation treatments for cancer, the cancer itself, surgical removal of the lymph nodes, or even tropical infection (lymphatic filariasis — elephantiasis). Secondary lymphedema often occurs wherever lymph nodes are surgically removed. It can also develop when the lymphatic system gets overloaded due to chronic skin infection, problems with blood vessels, or being overweight.

SYMPTOMS OF LYMPHEDEMA

Common symptoms associated with lymphedema include:

  • Progressive swelling in the leg or arm, which may include the fingers and toes
  • Heaviness or tightness in the affected limb
  • Aching or pains
  • Infections that recur
  • The skin hardens or thickens (fibrosis)

Swelling from lymphedema can range from mild to severe. If swelling is severe there may be range of motion restrictions. Also important to note is that symptoms of lymphedema caused by cancer treatments may not happen for months or even years after treatment is delivered.

RISK FACTORS FOR LYMPHEDEMA

There are a number of risk factors that pertain to secondary lymphedema, including:

  • Advanced age
  • Overweight/obesity
  • Arthritis (rheumatoid or psoriatic)
  • If you have cancer or have had cancer treatments in the past
  • Some types of infections

DIAGNOSING LYMPHEDEMA

Diagnosis of lymphedema begins with a physical examination of the affected limb or area, as well as an exploration of your health history. If you have had a pre-adult history of leg swelling but no pain, this could suggest lymphedema. Additionally, swelling that develops after damage to the lymph nodes (or their surgical removal) may indicate lymphedema. A vascular surgeon or specialist may call for imaging tests of the lymphatic system to help determine the appropriate treatment protocols.

Imaging tests used to help with diagnosis may include:

  • MRI
  • CT Scan
  • Duplex Ultrasound
  • Lymphoscintigraphy

TREATING LYMPHEDEMA

Diseases and disorders of the lymphatic system are typically treated by immunologists. Vascular surgeons, dermatologists, oncologists and physiatrists also get involved in treatment of various lymphatic ailments. Because there is no cure for lymphedema, per se, the treatment protocols generally focus on reducing swelling and pain in the affected areas.

Lymphedema may be treated in the following ways:

  • Exercise as prescribed by your doctor
  • Wrapping the arms or legs
  • Manual lymph drainage
  • Pneumatic compression and compression stockings

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